Joe Biden included Irish Taoiseach Micheál Martin in his first calls to European leaders as President-elect.
Biden also made calls to Prime Minister Boris Johnson, French President Emmanuel Macron, German Chancellor Angela Merkel.
Ireland has become a sticking point in Brexit negotiations recently.
The government’s controversial Internal Market bill has drawn criticism for potentially undermining the Good Friday Agreement.
Joe Biden is vocally proud of his Irish heritage and warned that these tensions could affect US-UK relations.
How will Ireland affect relations between the US and the UK?